I'm starting to play with v10 and I'll post some first impressions soon but I went looking for the Dex.ini file today to change a setting only to find out that it's moved! No forwarding address, no housewarming party for the new location, nothing.
Well, it's now at c:\program files\microsoft dynamics\gp\data\dex.ini by default. So now you know. Check out my Dex.ini post for more info.